Endocrine Abstracts

Testicular adrenal rest tumors (TARTs) are benign masses causing testicular damage and infertility. Their development is attributed to chronic stimulation of elevated ACTH levels. Several diseases are characterized by an increase of ACTH, however TARTs have been described almost exclusively in patients with congenital adrenal hyperplasia (CAH), excluding only rare cases. X-linked adrenoleukodystrophy (X-ALD) is a rare cause of primary adrenal insufficiency (PAI). It is a genet...

Context: Fludrocortisone (FC) is the mineralocorticoid (MC) replacement treatment for patients with primary adrenal insufficiency (PAI). Objective: To explore the dose of FC treatment and its relationship with glucocorticoid therapy, sodium, potassium, renin and clinical parameters. Design: Longitudinal study.Setting: Monocentric cohort.Patients: Data of 193 patients with PAI (130 autoi...

Introduction: Adrenal crisis (AC) is the most severe manifestation of adrenal insufficiency, still responsible for a high mortality of affected patients, especially with primary adrenal insufficiency (PAI). Its presentation is insidious, leading to a delayed diagnosis and treatment. Patient education is crucial in the prevention and self-management of AC.Aim of the study: We want to evaluate the incidence, features (symptoms, signs, laboratory findings),...